VDR is a Virtual Data Room that provides secure access to secure documents related to business transactions. VDRs can be used to perform due diligence in mergers and acquisitions. They also help businesses organize important documents and share them with investors and other stakeholders. VDRs can also be used to store and manage contracts, invoices and other documents for legal purposes such as litigation and estate planning.

Members should review their current procedures and the equipment for their vessels that have VDR/SVDR installed. It is also recommended to to upgrade and replace the equipment that is outdated or that are not in compliance with the minimum safety requirements.

The active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)2D), binds to the vitamin D receptor (VDR) and retinoid X receptor (RXR) to form heterodimers that act on gene promoter regions known as vitamin D response elements. These genes regulate the expression of proteins that are involved in a variety of physiological processes.

The VDR is located in glial cells and subsets them that comprise the brain. In the hippocampal cells of the rat primary it was observed that immunoreactivity for VDR was observed in the oligodendrocytes. The VDR is also present in human neuroblastoma as well as astrocytes. Treatment of HL-60 myeloblast leukemia cells with 1,25(OH)2D3 caused monocyte-like differentiation and increased VDR protein levels. This effect was reversible by inhibitors of the PI3K and MAPK pathways. In addition, VDR expression was increased in oligodendrocytes treated with 12-O-tetradecanoylphorbol-13-acetate (TPA) to induce megakaryoblastic leukemia cell maturation.